THE THERAPEUTIC PROBIOTIC For the dietary management of ulcerative colitis (UC), irritable bowel syndrome (IBS), and pouchitis.
As a probiotic medical food, VSL#3® is specially formulated and processed to provide a precise mixture of certain bacterial species with potential synergistic relationships. The importance of the gastrointestinal microflora in the normal functioning of the human gastrointestinal tract is well recognized. Several studies demonstrate that patients with IBS, UC or an ileal pouch have decreased luminal concentrations of lactobacilli and bifidobacteria compared with healthy individuals. Patients with IBS, UC or an ileal pouch may benefit from consuming high levels of probiotic bacteria so as to maintain the appropriate quantity and balance of beneficial microflora in their gastrointestinal tract. This is particularly important for patients with UC or an ileal pouch in view of their frequent and often long term antibiotic treatment. Hence, IBS, UC and ileal pouch patients have a distinct nutritional requirement that differs from normal individuals. Daily consumption of high levels of probiotic bacteria is needed to maintain adequate and balanced colonization in the gastrointestinal tract, and this cannot be achieved simply by modification of the normal diet.